with 9 state-of-the-art technological platforms
We provide expert support and analysis services, as well as the development of bioinformatics pipelines and interfaces to process and visualize a range of genetics, genomics and epigenomics data.
Our pipelines are built using a variety of tools chosen to ensure scalability, reproducibility and portability (workflow manager snakemake, package manager Conda, container manager Docker). Graphical Shiny/R applications provide users with efficient means to explore their results.
Our activity is tightly linked with the sequencing data production at the iGenSeq core facility.
Techniques
We provide support in the analysis of most high-throughput sequencing acquisition (NGS) techniques, including:
- Whole-exome sequencing
- Whole-genome sequencing
- Gene panel
- Bulk RNA-seq
- Long non-coding RNA
- MicroRNA
- Single-cell RNAseq, single-cell multiome (10X Genomics)
- Bisulfite-seq (methylation profile)
- ATAC-seq (chromatin accessibility)
- ChIP-seq (protein binding)
- Long-reads sequencing (Oxford Nanopore, transcriptomics)
- GWAS, transcriptomics, methylation
- Spatial Transcriptomics (10X Visium, Visium HD & Xenium)
Internal tools developped at Data Analysis Core
- DEJAVU, a tool which aggregates exome and genome sequencing short variants of 3000 samples from ICM projects (ICM only)
- QUBY, a tool to explore yourself RNAseq, single-cell or WES data analyzed by DAC
GEO submissions
We assist researchers in uploading their data to GEO to share their data with their publications. We do so once per month. To ensure timely registration please request so at least one month in advance. Last minute requests (< 30 days) are subject to billing. Please find instructions for GEO submission here.
Contact information
Please use this form to request analysis services. For further questions, please contact us at dac_omics@icm-institute.org.